Complement System ·
Three Pathways → MAC Pore
un
seel
.com · ~30 plasma proteins · C3 → C5b-9
C3 plasma
~1 mg/mL
MAC pore
~10 nm
Stage
idle plasma
Classical (antibody-bound)
Lectin (MBL on sugars)
Alternative (tickover)
C5b-9 MAC pore
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.com · Complement System