Liquid-Liquid Phase Separation ·
The Cell as an Emulsion
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.com · Membraneless Biomolecular Condensates
Threshold
~1–10 µM
Made of
multivalent IDR + RNA
State
dilute
IDR protein (sticky patches)
Condensate droplet (liquid)
Hardened → fibril (disease)
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.com · Liquid-Liquid Phase Separation