Non-Homologous End Joining · Template-free DSB repair
unseel.com · Ku70/80  ·  DNA-PKcs  ·  Artemis  ·  Ligase IV
Stage
Breaks/day 10–50
operation
DNA duplex (broken)
Ku70/80 ring
DNA-PKcs kinase
Artemis nuclease
XRCC4–Ligase IV
Unseel.com · Non-Homologous End Joining