PI3K-Akt Pathway ·
A Membrane Lipid Switch
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.com · PIP2 → PIP3 · Akt / PKB · PTEN
PIP3 level
low
Akt state
off
Event
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PIP2 lipid (resting)
PIP3 lipid (signal)
PI3K · PDK1 · mTORC2
Akt / PKB
PTEN (eraser)
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