Unfolded Protein Response ·
ER Stress · Sensors · Fate
un
seel
.com · proteostasis · IRE1 · PERK · ATF6
ER stress
low
Chaperones
baseline
Phase
—
folded protein
misfolded protein
BiP chaperone
UPR sensor (IRE1/PERK/ATF6)
ribosome / translation
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.com · Unfolded Protein Response