The Appel Reaction ·
R-OH → R-Br, room temperature
un
seel
.com · PPh₃ + CBr₄ · driven by the P=O bond
Config at C
R
Step
0
Stage
reagents assembled
Phosphorus (PPh₃)
Bromine
Oxygen (alcohol)
Carbon (substrate)
CBr₄ / ⁻CBr₃
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.com · The Appel Reaction