Biginelli Reaction · 3 Components, 1 Ring
unseel.com · RCHO + β-ketoester + urea → DHPM · 1893
Stage reactants
H₂O lost 0
step
Aldehyde (C4)
β-Ketoester
Urea (N-C(=O)-N)
N-acyliminium
DHPM ring
Unseel.com · Biginelli Reaction