The Friedländer Synthesis ·
Two Carbonyls → One Quinoline
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.com · 2-aminoaryl ketone + α-CH₂ carbonyl · 1882
new bonds
0 / 2
H₂O lost
0
stage
reactants assembled
aryl ring C
amino N
carbonyl O
α-CH₂ partner C
new bond
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.com · The Friedländer Synthesis