The Gabriel Synthesis ·
One-Shot Nitrogen
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.com · phthalimide → pure R-NH₂ · Gabriel 1887
N alkylations
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Product
—
Stage
phthalimide, N–H intact
Phthalimide C / ring
Nitrogen (the mask)
Carbonyl O
Alkyl group R / amine
Leaving group / hydrazine
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.com · The Gabriel Synthesis