Johnson-Claisen ·
Orthoester [3,3] Shift
un
seel
.com · allylic alcohol → γ,δ-unsaturated ester · Johnson 1970
Stage
assemble
Electrons
6 e⁻
Step
allylic alcohol + orthoester
Oxygen
Carbon
Allyl C=C → product C=O
Ketene acetal C=C
New C-C bond
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.com · Johnson-Claisen