Luche Reduction · NaBH₄ + CeCl₃, 1,2 over 1,4
unseel.com · enone → allylic alcohol · Luche 1978
Pathway
1,2 : 1,4
Stage enone assembled
Carbonyl O / C-2 (hard site)
Carbon skeleton
β-carbon C-4 (soft site)
Hydride (H⁻) from B
Ce³⁺ (hardens the hydride)
Unseel.com · Luche Reduction