MALDI-TOF ·
Weigh a Protein by Flight Time
un
seel
.com · laser + matrix → [M+H]⁺ → t ∝ √(m/z)
Stage
load
t of flight
— µs
operation
matrix + analyte co-crystal
Matrix (UV absorber)
Light peptide (fast)
Heavy protein (slow)
UV laser 337 nm
Detector / spectrum
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.com · MALDI-TOF