Malonic Ester Synthesis ·
R–X → R–CH₂–COOH
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.com · diethyl malonate · alkylate → hydrolyze → −CO₂
Stage
idle
α-C pK
a
13
Step
overview
Carbon
Oxygen
Hydrogen
α-C / enolate charge
Alkyl group R
Base / new bond / CO₂
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.com · Malonic Ester Synthesis