Oxy-Cope · Anionic [3,3] Shift
unseel.com · 3-hydroxy-1,5-diene → δ,ε-enone · up to 10¹⁷×
O state O-H
Rate boost
Stage 3-hydroxy-1,5-hexadiene
Carbon skeleton
Oxygen (O-H / O⁻)
Breaking C3-C4 σ bond
Forming C1-C6 σ bond
π electrons in flight
Unseel.com · Oxy-Cope Rearrangement