The Schmidt Reaction · Wedge a Nitrogen In
unseel.com · ketone + HN₃ → amide + N₂ · K. F. Schmidt, 1923
Intermediate ketone
N₂ lost 0
Step carbonyl at rest
Carbon (skeleton)
Oxygen
Nitrogen (inserted)
Migrating group R
Leaving N₂
Unseel.com · The Schmidt Reaction