Sharpless AD ·
Pick the Face, Pick the Enantiomer
un
seel
.com · alkene + OsO₄ + chiral ligand → syn-diol · Nobel 2001
Os state
Os(VIII)
ee
—
Stage
flat alkene, two faces
Alkene C=C
Osmium (Os)
Os=O oxygens
Chiral ligand (DHQD)
New OH / syn-diol
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.com · Sharpless Dihydroxylation