The Ullmann Reaction · Copper Biaryl Coupling
unseel.com · 2 Ar–I + Cu → Ar–Ar · since 1901
Cu state Cu(I)
Bonds forged 0
Stage two aryl iodides + copper
Copper (Cu)
Aryl ring (Ar)
Aryl ring (Ar′)
Iodide (I⁻)
New C–C bond
Unseel.com · The Ullmann Reaction