Ischemic
Penumbra
un
seel
.com · core · penumbra · CBF thresholds · time is brain
neurons lost
0
M
core
0
mL
penumbra
0
mL
state
—
Core — rCBF < 30% (dead, <10 mL/100g/min)
Penumbra — Tmax > 6 s (10–20 mL, salvageable)
Benign oligemia — > 20 mL/100g/min
Reperfused — rescued brain
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.com · The Ischemic Penumbra: Salvageable Brain in the Golden Hour