Nephrotic
Syndrome
un
seel
.com · podocyte · slit diaphragm · effacement · proteinuria
proteinuria
0.1
g/day
serum albumin
4.2
g/dL
barrier
intact
state
—
Filtration barrier: endothelium · GBM · podocyte
Albumin retained in the blood (healthy)
Slit diaphragm: nephrin · podocin zipper
Albumin leaking into urine (proteinuria)
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.com · Nephrotic Syndrome: How Podocyte Injury Unleashes Massive Proteinuria