Rh
Isoimmunization
un
seel
.com · fetomaternal hemorrhage · anti-D IgG · hemolysis · hydrops
anti-D titer
0
fetal Hb
normal
pregnancy
—
stage
—
Fetal RhD-positive red cells (the target)
Maternal circulation & B cells
Anti-D IgG (crosses via FcRn)
RhoGAM — antibody-mediated suppression
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.com · Rh Isoimmunization: How a Second Pregnancy Attacks Fetal Blood