Warfarin & the
Vitamin K Cycle
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.com · VKOR block · carboxylation · factor depletion · INR swing
INR
1.0
functional factors
4 / 4
VKOR
active
state
—
Vitamin K redox cycle (VKOR / VKORC1)
Carboxylated factors II · VII · IX · X (functional)
Warfarin block · under-carboxylated PIVKAs
INR tracing · therapeutic band 2.0–3.0
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.com · Warfarin and the Vitamin K Cycle: Why Your INR Swings